Pentraxin 3 in Systemic Lupus Erithematosus: Questions to be Resolved

نویسندگان

  • Roberto Assandri
  • Marta Monari
  • Alessandro Montanelli
چکیده

Citation: Assandri R, Monari M, Montanelli A. Pentraxin 3 in Systemic Lupus Erithematosus: Questions to be Resolved. Transl Biomed. 2015, 6:1. Systemic lupus erythematosus (SLE) is a autoimmune disorder with unpredictable course that involves polyclonal autoimmunity against multiple autoantigens and presents a broad spectrum of clinical manifestations (fever, skin rashes, arthralgia, inflammation of kidney, lungs, or brain) [1]. The pathogenesis of SLE is based on a combinations of genetic variants and environmental factors that promote loss-of-tolerance or tissue inflammation [2]. In fact there is growing evidence to suggest that inflammation and related molecules plays a key role in the pathogenesis of SLE.

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تاریخ انتشار 2016